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Launch Excellence Partners
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Patient Profiles

Developing patient profiles to inform development protocols and patient centricity

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Nurse and Patient

Effective treatments and improved outcomes rely on deep understanding of the different patient profiles.

The cause (etiology) of a disease or disorder, the mechanisms of its development (pathogenesis), the structural changes associated with the disease process (morphological changes), and the functional consequences of those changes are not black and white.
In addition to these, the genetic complexity of most diseases results in extremely heterogeneous clinical presentation.

Today, many diseases or disorders have been better described due to significant increase in scientific knowledge of that condition.

The incredibly large numbers of clinical trial failures for example in neurodegenerative diseases, demonstrated an incomplete knowledge of pathogenic pathways, and an even greater need to substantially improve patient stratification in clinical trials.

The development of the tailored care based on profiles consists of four steps: (1) identification of the target population, (2) assessment, (3) stratification, and (4) tailoring.

This approach results in subgroups of patients who are more homogeneous than the population in terms of care needs, abilities and preferences, while acknowledging that a certain amount of heterogeneity within these subgroups will remain.

We develop and validate a robust and feasible set of patient profiles that can be used to support more patient-centered protocol development and launch strategies.

We help you define the patient subgroups to be aligned with interventions

We help our clients make a meaningful impact on patients’ lives by really understanding the patient characteristics and demographics

Combining characteristics into a scientifically robust and practicably feasible set of patient profiles




Concomitant medication


Morbidity and mortality

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